Malmö Preventive Medicine

Name of biobank:

Malmö Preventive Medicine

General Information:

Prospective, observational population-based study with a baseline examination 1974-1991 (n = 33444), and follow up by registers and a re-examination 2002-2005. Initial limited interaction against hypertension hyperlipidemia, and high alcohol consumption. Main focus on cardiovascular disease, diabetes and cancer.

Responsible organisation:

Lunds Universitet

Responsible principle scientist:

Göran Berglund

Rules for acess:

A document describing the rules and guidelines for an access application will be added shortly. For the time being contact Göran Berglund.

Biobank content:

• Plasma 1 x 5 ml stored at –20°C
   
• Serum 1 x 5 ml stored at –20°C
   

Attached database:

Yes

Variables in database:

• Baseline examination
   
  • Questionnaire
     
    • Heredity
    • Occupation
    • Social-economy
    • Previous diseases
    • Medication
      
       
  • Measurements
     
    • BP, HR
    • Spirometry
    • OGGT
    • Anthropometry
      
       
• Follow-up
   
  • Six year examination
     
  • Year 2002 examination
     
• End-points
   
  • Mortality
     
  • Cancer events
     
  • Cardiovascular events
     
• Other morbidity
   
  • Other registers follow-up
     
  • X-ray
     
  • In hospital bed days
     
  • Relatives
     
  • Population and housing censuses
     

Up to five selected publications:

• G. Berglund, P. Nilsson, K.-F. Eriksson, J-Å. Nilsson, B. Hedblad, H. Kristensson, F. Lindgärde.
  Long-term outcome of the Malmö Preventive Project: mortality and cardiovascular morbidity
  J intern Med. 2000;247:19-29
   
• G. Berglund, K. F. Eriksson, B. Israelsson, T. Kjellström, F. Lindgärde, I. Mattiasson, J. Å. Nilsson, L. Stavenow
  Cardiovascular risk groups and mortality in an urban Swedish male population: the Malmö Preventive Project
  J intern Med. 1996;239:489-497
   

Role in National Biobanking programme:

1. Coordinates the work package on optimisation and quality control of DNA extraction (WP 4.1) methods from whole blood, serum, paraffin blocks etc.
    
2. Performs an improvement on the biobank infrastructure by a) systematic DNA extraction and arraying of all samples b)implements a formal quality control system c) provides data on usefulness of samples such as endpoints and quality documentation to the National Biobanking programme joint database.
    
3. Delivers samples for epidemiological research. A complete listing of samples delivered during 2002 will be posted here soon.